One doesn’t frequently have the opportunity to envision a mob of angry scientists, chanting slogans, lab coats a-flapping, brandishing acetylene torches and tuning forks, marching to storm the fortress of the status quo. However, this is precisely the image that has been conjured up in recent weeks (1) to describe the furious stream of blog posts, op-eds, and twitter streams emanating from the corner offices of labs across the country, denouncing prestigious journals and publishers as ‘enemies of science’ (2).