Sensopathy

Sensopathy

Last month, we asked you, the reader, which of the five major senses you find most interesting from a neuroscience perspective. We received the following response from guest contributor, Scott Jon Shagin. Here, Shagin describes each of the major senses from his experience living with multiple sclerosis and explains why he feels the one he picks is the most "interesting." His precise and punchy post is sure to delight, educate and enlighten.

(Photo Credit: Scott Shagin)

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Why do humans hallucinate on little sleep?

Why do humans hallucinate on little sleep?

What do psychosis, psychedelics and sleep deprivation have in common? They make you really bad at perceiving visual illusions…and really good at hallucinating.

Driven by bewilderment, a hunch, and a sense of purpose, I set out to determine how sleep deprivation causes visual hallucinations. My quest turned up a key paper (written entirely in German), a new hypothesis and a vow to get more sleep. Below is an exposition of my journey, beginning about a decade ago.

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Neurotalk S5E11: Okihide Hikosaka

Today, our guest is Okihide Hikosaka, a Senior Researcher and Section Chief at the National Eye Institute, at the National Institutes of Health in Bethesda, Maryland. We’ll be speaking with him about the role of speculation and intuition in science, the life histories and personalities of our monkey colleagues, and how short-term versus long-term memories inhabit different parts of the basal ganglia.

To understand the brain, meet the players involved: characterizing the cell types of the cortex

To understand the brain, meet the players involved: characterizing the cell types of the cortex

The number of cells in the human brain is a staggering figure. There are over a trillion cells if you count both neurons (the better-known cells that compute with electrical signals) and glia (cells that provide support and protection for neurons). But the complexity of the brain only becomes more mind-boggling once you recognize that these cells have remarkably different appearances, genetic signatures, and electrical functions. 

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Neurotalk S5E10: Bernardo Sabatini

Today, our guest is Professor Bernardo Sabatini, the Alice and Rodman W. Moorhead III Professor of Neurobiology at Harvard University. In this episode, we will talk about overcoming technological barriers, scientific bloodlines, and when the music industry meets science.

(P.S. The music video to which Prof. Sabatini refers: http://mssngpeces.com/projects/interactive/chairlift-met-before/)

All different and yet the same: searching for biological similarities between individuals with autism

“If you know one child with autism,” the saying goes, “you know one child with autism.” Though an estimated 1 in 68 children in the United States will be diagnosed with Autism Spectrum Disorder (ASD), their diverse personalities seem to defy categorization. Yet, dating back to the first report on ASD by Austrian-American psychiatrist Leo Kanner, clinicians have identified clear themes in the children’s behavior. Researchers have long struggled to pinpoint the common biological pathway underlying these behavioral commonalities seen in ASD. A study published last year by Silvia De Rubeis and her colleagues took advantage of rare risk variants to find molecular commonalities that underlie the behavioral traits that link autism spectrum disorders together. 

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